Mots-C 10mg
$75.00
MOTS-C
Dosage-Administration-Storage
MOTS-c is a 16–amino-acid mitochondrial-derived peptide (MDP) that acts as a metabolic regulator, primarily through AMPK activation. Preclinical studies show it enhances insulin sensitivity, promotes fat oxidation, improves exercise capacity, and counters age-related metabolic decline. This educational protocol presents a once-daily subcutaneous injection with gradual titration over a 10 week period.
- Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.
- Typical daily range: 200–1,000 mcg once daily (gradual titration over 10 weeks).
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U‑100 insulin syringe.
- Storage: Lyophilized: freeze at (−4 °F) or below; after reconstitution, refrigerate at (35.6–46.4 °F) and use within 7 days for best potency.
Description
MOTS-c (Mitochondrial Transcript-Encoded Small peptide c) is a naturally occurring peptide produced during exercise that helps regulate metabolism, improve insulin sensitivity, and boost physical performance by enhancing mitochondrial function, with research showing benefits for fat loss, anti-aging, and conditions like diabetes in animal studies, though it’s currently an experimental substance not FDA-approved for human use and banned in sports.
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Origin:
A small peptide encoded by the mitochondrial 12S rRNA gene, released by mitochondria in response to exercise.
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Function:
It acts as a signal, mimicking exercise and caloric restriction to improve how cells use fuel (glucose, fatty acids) and enhance metabolic flexibility.
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Mechanism:Activates AMPK (a key energy sensor), improves mitochondrial density, and helps prevent fat buildup in muscles, leading to better insulin sensitivity.


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