Description
MOTS-c is a 16-amino-acid peptide encoded within mitochondrial DNA that regulates metabolic homeostasis, insulin sensitivity, and cellular stress responses. Often studied as an “exercise mimetic,” it activates the AMPK pathway to help control glucose and fat metabolism.
Key Characteristics
- Origin: Derived from mitochondrial 12S rRNA.
- Mechanism: Activates AMPK energy-sensing pathways and supports metabolic flexibility.
- Research Focus: Investigated for potential roles in aging, insulin resistance, and physical performance.
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